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View Resource Imatinib (Gleevec) as a Paradigm of Targeted Cancer Therapies

Three lecture type video clips introduce about Chronic Myeloid Leukemia (CML) and Imatinib. The first lecture presents historical perspective on CML, clinical description of CML, and development of Imatinib and its clinical trials. The second one introduces the mechanism of relapse of Imatinib. The third one discusses new therapies for patients with Imatinib resistance.

http://www.ibiology.org/ibioseminars/cancer-medicine/brian-d...
View Resource Thalidomide Case Study

This is a case study adapted from "Teaching Chemistry Through the Jigsaw Strategy" by the Quality Education Fund, Hong Kong (2007). It brings to attention the importance of chirality and the structures of molecules in a biological context. It describes the real events surrounding the drug Thalidomide before it was pulled off of the market. This drug has recently been introduced back to the market...

https://clse-cwis.asc.ohio-state.edu/thalidomide_case_study
View Resource Antibiotic Resistance Teachable Tidbit…an Evolutionary Perspective

This activity utilizes the emergence of antibiotic resistance, and mechanisms thereof, to teach essential concepts including natural selection, bacterial gene transfer, mutation, and gene expression. It also provides a connection between course content and modern applications of important concepts. The activity (app. 25 minutes) is intended for introductory students in biology. It is flexible and...

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http://clse-cwis.asc.ohio-state.edu/teachable_tidbits/antibi...
View Resource Biotechnology Active Learning Teachable Tidbit

In this activity, students are exposed to some of the most significant biomolecules currently exploited by technology and identify their natural origins. They also explain the significance of the roles these biomolecules play in nature, as well as for humans. Specifically, students work to develop a logical process for a real-life application of biotechnology (insulin production) using knowledge...

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http://clse-cwis.asc.ohio-state.edu/teachable_tidbits/biotec...
View Resource HIV Resistance

This 3D animation explains in detail how and why HIVs develop drug resistance in a short period of time.

http://mx.youtube.com/watch?v=TvNOmwRh0I0
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