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Imatinib (Gleevec) as a Paradigm of Targeted Cancer Therapies
Three lecture type video clips introduce
about Chronic Myeloid Leukemia (CML) and Imatinib. The first lecture presents historical perspective on CML, clinical description of CML, and development of Imatinib and its clinical trials. The second one introduces the mechanism of relapse of Imatinib. The third one discusses new therapies for patients with Imatinib resistance.
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http://www.ibiology.org/ibioseminars/cancer-medicine/brian-d...
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Thalidomide Case Study
This is a case study adapted from "Teaching Chemistry Through the Jigsaw Strategy" by the Quality Education Fund, Hong Kong (2007). It brings to attention the importance of chirality and the structures of molecules in a biological context. It describes the real events surrounding the drug Thalidomide before it was pulled off of the market. This drug has recently been introduced back to the market...
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https://clse-cwis.asc.ohio-state.edu/thalidomide_case_study
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Antibiotic Resistance Teachable Tidbit…an Evolutionary Perspective
This activity utilizes the emergence of antibiotic resistance, and mechanisms thereof, to teach essential concepts including natural selection, bacterial gene transfer, mutation, and gene expression. It also provides a connection between course content and modern applications of important concepts. The activity (app. 25 minutes) is intended for introductory students in biology. It is flexible and...
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http://clse-cwis.asc.ohio-state.edu/teachable_tidbits/antibi...
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Biotechnology Active Learning Teachable Tidbit
In this activity, students are exposed to some of the most significant biomolecules currently exploited by technology and identify their natural origins. They also explain the significance of the roles these biomolecules play in nature, as well as for humans. Specifically, students work to develop a logical process for a real-life application of biotechnology (insulin production) using knowledge...
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http://clse-cwis.asc.ohio-state.edu/teachable_tidbits/biotec...
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HIV Resistance
This 3D animation explains in detail how and why HIVs develop drug resistance in a short period of time.
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http://mx.youtube.com/watch?v=TvNOmwRh0I0
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