This is a one-day teachable unit with pre and post-class activities. Materials in this teachable unit are geared towards introducing epigenetics as a form of non-genetic inheritance to students who have little or no prior knowledge of epigenetics. Students are however expected to have a basic understanding of the central dogma: replication, transcription, translation, and their regulatory mechanisms. Students should also have a background on packaging of DNA into chromatin, and the difference between euchromatin and heterochromatin. In addition, students will be asked to perform a pre-class ‘Lick Your Rat’ interactive online activity as an introduction to epigenetics (Lick Your Rat Resource located at http://learn.genetics.utah.edu/content/epigenetics/rats/ & General resource attribution: Genetic Science Learning Center, University of Utah, http://learn.genetics.utah.edu ). In this activity, students act as a mother rat and discover how epigenetic changes experienced by the rat pups relate to the degree of nurturing that they experience. Additional resource components found on this site help students learn the molecular changes associated with epigenetic modifications, as well as additional information related to this concept, and serves as an excellent introductory exercise for this teachable tidbit.
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