The Surface Area : Volume worksheet is a relatively short (7-question) worksheet that can be used to assess the degree to which students grasp the relationship between surface area and volume, as well as the significance of this relationship to cellular structure and function. Questions are posed in short-answer form, though multiple questions can be answered with a single word. This resource has previously been used as part of a plant diversity lecture for majors. However, the content is also appropriate for a more general discussion or lecture on cellular structure and function for both majors and non-majors. While the worksheet could be assigned to individual students (likely as homework outside of class), it may be more effectively utilized as an in-class activity in which pairs or small groups of students work together to discuss and respond to the questions posed.